Sign in →

Test Code DOC11 11-Deoxycortisol, Serum

Secondary ID


Useful For

Diagnostic workup of patients with congenital adrenal hyperplasia


Part of metyrapone testing in the workup of suspected secondary or tertiary adrenal insufficiency


Part of metyrapone testing in the differential diagnostic workup of Cushing syndrome

Testing Algorithm

See Steroid Pathways in Special Instructions.

Special Instructions

Method Name

Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS)

Reporting Name

11-Deoxycortisol, S

Specimen Type


Necessary Information

Indicate if specimen was drawn before or after metyrapone.

Specimen Required


Preferred: Red top

Acceptable: Serum gel

Specimen Volume: 0.5 mL

Collection Instructions: Morning (8 a.m.) specimen is preferred.

Specimen Minimum Volume

0.4 mL

Specimen Stability Information

Specimen Type Temperature Time
Serum Refrigerated (preferred) 28 days
  Ambient  28 days
  Frozen  28 days

Reject Due To


Mild OK; Gross reject


Mild OK; Gross OK


Mild OK; Gross OK



Reference Values

≤18 years: <344 ng/dL

>18 years: 10-79 ng/dL

Day(s) and Time(s) Performed

Tuesday; 10 a.m.

Performing Laboratory

Mayo Medical Laboratories in Rochester

Test Classification

This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the U.S. Food and Drug Administration.

CPT Code Information


LOINC Code Information

Test ID Test Order Name Order LOINC Value
DCORT 11-Deoxycortisol, S In Process


Result ID Test Result Name Result LOINC Value
46923 11-Deoxycortisol, S 1657-6