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Test Code A1ATCL Alpha-1-Antitrypsin Clearance, Feces and Serum

Important Note

Both serum and feces required. Stool collection can be 24,48, or 72 hours. Document time frame

MAYO STOOL CONTAINERS MUST BE USED.


Advisory Information


The recommended procedure for protein-losing enteropathy is A1AFS / Alpha-1-Antitrypsin Clearance, Feces and Serum.



Shipping Instructions


Feces and serum should be shipped together. Specimens shipped separately may delay testing.



Specimen Required


Both feces and serum are required.

 

Blood must be drawn during the stool collection period.

 

Specimen Type: Serum

Collection Container/Tube: Red top or serum gel

Submission Container/Tube: Plastic vial

Specimen Volume: 1 mL

Collection Instructions:

1. Centrifuge within 2 hours.

2. Aliquot and ship in plastic vial.

 

Specimen Type: Feces

Supplies: Stool Containers - 24, 48, 72 Hour Kit (T291)

Specimen Volume: Entire collection

Collection Instructions:

1. Collect a 24-hour fecal collection.

2. If no specimen is obtained within 24 hours, extend collection time to 48 to 72 hours. Document time frame.


Secondary ID

604982

Useful For

Diagnosing protein-losing enteropathies

Profile Information

Test ID Reporting Name Available Separately Always Performed
AATS Alpha-1-Antitrypsin, S No Yes
A1ATF Alpha-1-Antitrypsin, 24 Hr, F No Yes

Method Name

Nephelometry

Reporting Name

Alpha-1-Antitrypsin Clearance

Specimen Type

Fecal
Serum

Specimen Minimum Volume

Homogenized feces: 1 mL
Serum: 0.5 mL

Specimen Stability Information

Specimen Type Temperature Time
Fecal Frozen (preferred) 14 days
  Ambient  14 days
  Refrigerated  14 days
Serum Frozen (preferred) 28 days
  Ambient  28 days
  Refrigerated  28 days

Reject Due To

Gross hemolysis

OK

Gross lipemia

OK

Gross icterus

OK

Feces

Collected in any preservative or fixative

Reference Values

CLEARANCE:

≤27 mL/24 hours

 

FECAL ALPHA-1-ANTRYPSIN CONCENTRATION:

≤54 mg/Dl

 

SERUM ALPHA-1-ANTRYPSIN CONCENTRATION:

100-190 mg/dL

Day(s) and Time(s) Performed

Monday through Saturday; 2 p.m.

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Test Classification

This test has been modified from the manufacturer's instructions. Its performance characteristics were determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the U.S. Food and Drug Administration.

CPT Code Information

82103 x 2

LOINC Code Information

Test ID Test Order Name Order LOINC Value
A1AFS Alpha-1-Antitrypsin Clearance 93419-0

 

Result ID Test Result Name Result LOINC Value
AAT24 Alpha-1-Antitrypsin, 24 Hr, F 9407-8
AATS Alpha-1-Antitrypsin, S 6771-0
CRCLR Clearance 18271-7