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Test Code CLBAZM Clobazam and Metabolite, Serum


Specimen Required


Collection Container/Tube: Red top

Submission Container/Tube: Plastic vial

Specimen Volume: 0.5 mL

Collection Instructions:

1. Draw specimen immediately before next scheduled dose.

2. Spin down within 2 hours of draw and move serum to plastic vial.

3. Trough specimens are recommended as therapeutic ranges are based on specimens drawn at trough (ie, immediately before the next dose).


Secondary ID

65483

Useful For

Monitoring clobazam therapy

Method Name

Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS)

Reporting Name

Clobazam and metabolite, S

Specimen Type

Serum Red

Specimen Minimum Volume

0.35 mL

Specimen Stability Information

Specimen Type Temperature Time
Serum Red Refrigerated (preferred) 28 days
  Ambient  28 days
  Frozen  28 days

Reject Due To

Hemolysis

Mild OK; Gross OK

Lipemia

Mild OK; Gross OK

Icterus

Mild OK; Gross OK

Other

NA

Reference Values

CLOBAZAM

Therapeutic Range: 30-300 ng/mL

 

NORCLOBAZAM

Therapeutic Range: 300-3,000 ng/mL

Day(s) and Time(s) Performed

Monday-Friday; 5 p.m.

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Test Classification

This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the U.S. Food and Drug Administration.

CPT Code Information

80339 (G0480 if appropriate)

LOINC Code Information

Test ID Test Order Name Order LOINC Value
CLOBZ Clobazam and metabolite, S 79408-1

 

Result ID Test Result Name Result LOINC Value
65483 Clobazam 3487-6
92363 N-desmethylclobazam 35107-2