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Test Code Nipple Discharge Nipple Discharge Cytology

Collection Container

Cytology fixative container (PreservCyt®)

Specimen Required

Nipple Discharge

Transport Temperature

Room Temperature

Specimen Stability

Stable in proper fixative

Reasons for Rejection

Improper fixation; air drying artifact; unlabeled container; failure to include pertinent history

Reference Ranges

Negative to abnormal cells consistent with malignant neoplasm

Turnaround Time

24-48 hours; for same day processing, specimens must be received by 2 PM.

Day(s) and Time(s) Performed

Mon-Fri, 7:30 AM-5PM

Additional Information

Collection:  Uncap the fixative container to facilitate rapid fixation of the specimen.  Specimen is collected by gently massaging the breast in the direction of the nipple.  Allow secreted drops to fall directly into the fixative container.  Once all available material is expressed, recap the specimen container.  Fill out a cytology requisition and label specimen container including all pertinent patient information, name, medical record number, date of birth, physician and specimen type, including laterality.

CPT Code


Other Acceptable Specimen Types

CytoLyt® Solution

Special Handling Instructions

Limitations:  Allowing specimen to air dry prior to fixation will render it unsatisfactory for interpretation.