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Test Code TLCU Immunoglobulin Total Light Chains, Urine

Reporting Name

Immunoglobulin Total Light Chains,U

Useful For

Monitoring patients whose urine demonstrates large M-spikes

 

Confirming the quantitation of specimens that show M-spikes by electrophoresis

 

Detecting urine monoclonal proteins and identification of specimens that need urine protein electrophoresis

Profile Information

Test ID Reporting Name Available Separately Always Performed
KTLCU Kappa Total Light Chain, U No Yes
LTLCU Lambda Total Light Chain, U No Yes
KLTRU Kappa/Lambda TLC Ratio, U No Yes

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Specimen Type

Urine


Specimen Required


If serum is being submitted on the same patient for FLCP / Immunoglobulin Free Light Chains, Serum; order that test under a different order.

 

Submit only 1 of the following specimens:

 

Specimen Type: Random urine

Supplies: Urine Tubes, 10 mL (T068)

Container/Tube: Plastic, 10-mL urine tube

Specimen Volume: 1 mL

Collection Instructions: Collect a random urine specimen.

 

Specimen Type: 24-Hour urine

Supplies: Urine Tubes, 10 mL (T068)

Container/Tube: Plastic, 10-mL urine tube

Specimen Volume: 1 mL

Collection Instructions: Collect urine for 24 hours.


Specimen Minimum Volume

0.5 mL

Specimen Stability Information

Specimen Type Temperature Time
Urine Refrigerated (preferred) 7 days
  Frozen  20 days
  Ambient  72 hours

Reference Values

KAPPA TOTAL LIGHT CHAIN

<0.9 mg/dL

 

LAMBDA TOTAL LIGHT CHAIN

<0.7 mg/dL

 

KAPPA/LAMBDA RATIO

0.7-6.2

Day(s) and Time(s) Performed

Monday through Saturday; Continuously until 3 p.m.

Test Classification

This test has been modified from the manufacturer's instructions. Its performance characteristics were determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the U.S. Food and Drug Administration.

CPT Code Information

83883 x 2

LOINC Code Information

Test ID Test Order Name Order LOINC Value
TLCU Immunoglobulin Total Light Chains,U In Process

 

Result ID Test Result Name Result LOINC Value
KLTRU Kappa/Lambda TLC Ratio, U 33559-6
KTLCU Kappa Total Light Chain, U 27365-6
LTLCU Lambda Total Light Chain, U 27394-6

Reject Due To

Hemolysis

NA

Lipemia

NA

Icterus

NA

Other

NA

 

Method Name

KTLCU, LTLCU: Nephelometry

Urine Preservative Collection Options

Note: The addition of preservative or application of temperature controls must occur within 4 hours of completion of the collection.

Ambient

Yes <72 hours

Refrigerate

Preferred

Frozen

Yes

50% Acetic Acid

No

Boric Acid

No

Diazolidinyl Urea

No

6M Hydrochloric Acid

No

6M Nitric Acid

No

Sodium Carbonate

No

Thymol

No

Toluene

No

Secondary ID

87934