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HelpTest Code UCORT Cortisol, Free, 24 Hour, Urine
Necessary Information
24-Hour volume is required.
Specimen Required
Supplies: Urine Tubes, 10-mL (T068)
Submission Container/Tube: Plastic, urine tube (T068)
Specimen Volume: 5 mL
Collection Instructions:
1. Collect urine for 24 hours.
2. Add 10 g of boric acid as preservative at start of collection.
Additional Information: See Urine Preservatives-Collection and Transportation for 24-Hour Urine Specimens in Special Instructions for multiple collections.
Secondary ID
8546Useful For
Preferred screening test for Cushing syndrome
Diagnosis of pseudo-hyperaldosteronism due to excessive licorice consumption
This test has limited usefulness in the evaluation of adrenal insufficiency
Special Instructions
Method Name
Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS)
Reporting Name
Cortisol, Free, USpecimen Type
UrineSpecimen Minimum Volume
3 mL
Specimen Stability Information
| Specimen Type | Temperature | Time |
|---|---|---|
| Urine | Refrigerated (preferred) | 14 days |
| Frozen | 28 days | |
| Ambient | 7 days |
Reject Due To
|
Hemolysis |
NA |
|
Lipemia |
NA |
|
Icterus |
NA |
|
Other |
NA |
Reference Values
0-2 years: not established
3-8 years: 1.4-20 mcg/24 hours
9-12 years: 2.6-37 mcg/24 hours
13-17 years: 4.0-56 mcg/24 hours
≥18 years: 3.5-45 mcg/24 hours
Use the factor below to convert from mcg/24 hours to nmol/24 hours:
Conversion factor
Cortisol: mcg/24 hours x 2.76=nmol/24 hours (molecular weight=362.5)
For SI unit Reference Values, see https://www.mayocliniclabs.com/order-tests/si-unit-conversion.html
Day(s) and Time(s) Performed
Monday through Friday; 4 p.m.
Performing Laboratory
Mayo Clinic Laboratories in Rochester
Test Classification
This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the U.S. Food and Drug Administration.CPT Code Information
82530
LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| CORTU | Cortisol, Free, U | 43126-2 |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| 8546 | Cortisol, U | 2147-7 |
| TM93 | Collection Duration | 13362-9 |
| VL47 | Urine Volume | 3167-4 |